3 3 difluorocyclopentanecarboxylic acid 75 solution in EtOAc and CH2Cl2 1 tert butoxycarbonyl 3 fluoropiperidine 4 carboxylic acid 1 1 9H fluoren 9 yl methoxy carbonyl pyrrolidin 3 yl piperidine 3 carboxylic acid 1 tert butyl 4 ethyl 3 3 difluoro 4 methylpiperidine 1 4 dicarboxylate 1 benzyl 4 fluoropiperidin 3 yl methanol 1 benzyl 3 methyl 5 5 difluoropiperidine 1 3 dicarboxylate 3 3 difluoropiperidin 4 ol hydrochloride 1 tert butyl 3 ethyl 5 5 difluoropiperidine 1 3 dicarboxylate 9 4 bromobutyl 9H fluorene 9 carboxylic acid 1 N Boc 4 fluoropiperidine 6 fluoro 3 piperidin 4 yl 1H indazole hydrochloride 3 trifluoromethyl piperidin 3 ol hydrochloride 8 Boc 2 fluoro 8 aza bicyclo 3 2 1 octan 3 ol 4 benzyl methyl amino 3 5 difluorobenzoic acid 2 1 tert butoxycarbonyl 3 3 difluoropiperidin 4 yl acetic acid 1 tert butyl 3 methyl 4 trifluoromethyl 5 6 dihydropyridine 1 3 4H dicarboxylate 4 dimethylamino 3 5 difluorobenzoic acid 4 chloro 3 fluoropyridine 2 2 2 trifluoro 1 piperazin 1 yl ethanone hydrochloride 1 benzyl 3 trifluoromethyl piperidin 4 ol 2 2 difluoropentanedioic acid 1 benzyl 3 trifluoromethyl piperidin 4 one 3 trifluoromethyl pyrrolidine hydrochloride 2 TRIFLUOROMETHOXY ETHYLAMINE HYDROCHLORIDE 3 4 Cis 1 tert butyl 4 methyl 3 fluoropiperidine 1 4 dicarboxylate racemate 1 benzyl 3 fluoro 1 2 5 6 tetrahydropyridin 4 yl methanol 1 amino 3 fluoropropan 2 ol hydrochloride 3 3 difluoro 1 4 bipiperidine dihydrochloride 9 9 butane 1 4 diyl bis 9H fluorene 9 carboxylic acid 1 N Boc 4 4 difluoropiperidine

4 4 difluoro 1 hydroxymethyladmantane 4 fluoro 1 hydroxymethyl admantane 3 3 difluoro 4 4 fluorobenzyl piperidine hydrochloride 5 5 difluoropiperidin 3 yl methanol hydrochloride 3 acetamido 2 nitrophenyl 4 dimethylamino 3 5 difluorobenzoate 3 acetamido 2 nitrophenyl 4 benzyl methyl amino 3 5 difluorobenzoate 3 acetamido 6 acetyl 2 nitrophenyl 4 benzyl methyl amino 3 5 difluorobenzoate 7 7 difluoro 4 5 6 7 tetrahydro 1H pyrazolo 4 3 c pyridine hydrochloride 3 Iodo 2 phenoxypyridine 3S 4R 1 tert butoxycarbonyl 3 fluoropiperidine 4 carboxylic acid enantiomer b 87 e e 5 5 difluoropiperidin 2 yl methanol hydrochloride 3 4 Trans 1 tert butyl 4 methyl 3 fluoropiperidine 1 4 dicarboxylate racemate 2 ethyl 4 4 difluoropyrrolidine 2 carboxylic acid hydrochloride 1 tert butyl 2 methyl 2 ethyl 4 4 difluoropyrrolidine 1 2 dicarboxylate 2 1 tert butoxycarbonyl 4 4 difluoropyrrolidin 3 yl acetic acid 3 fluoropiperidine 4 carboxylic acid hydrochloride 1 benzyloxycarbonyl 5 fluoropiperidine 3 carboxylic acid 1 tert butyl 4 ethyl 3 fluoro 4 methylpiperidine 1 4 dicarboxylate isomer B 1 2 difluoro 3 methoxy 5 nitrobenzene 4 5 dibromo 2 3 difluorobenzaldehyde 4 4 difluoropiperidin 3 yl acetate hydrochloride 1 tert butyl 2 methyl 5 5 difluoropiperidine 1 2 dicarboxylate 5 FLUORO 1 METHYL 3 4 PIPERIDINYL 1HINDAZOLE HYDROCHLORIDE 2 2 2 trifluoro 1 piperidin 3 yl ethanamine dihydrochloride 6 benzyl 2 4 dichloro 8 8 difluoro 5 6 7 8 tetrahydropyrido 4 3 d pyrimidine HYDROCHLORIDE 1 benzyl 3 3 difluoropiperidin 4 one oxime 3 bromo 1 methylpyridinium iodide 4 pyridin 4 yl pyrimidin 2 ol 3 5 dimethoxypyridine hydrochloride 3 5 benzyloxy carbonyl amino pyridin 3 yl propanoic acid

1 benzyl 4 bromopyridin 1 ium bromide 1 1 Boc piperidin 4 yl indole 4 Pyridin 3 ylsulfanyl piperidine 1 carboxylic acid tert butyl ester 1 N Boc 4 Mercaptopiperidine 4 Pyridin 4 ylsulfanyl piperidine 1 carboxylic acid tert butyl ester 1 BENZYLPIPERIDIN 4 YL ACETONITRILE 1 N BOC 4 METHANESULFONYLOXYMETHYLPIPERIDINE 1 benzyl 3 bromopiperidin 4 one HBr salt 1 N BOC 3 METHANESULFONYLOXYMETHYLPIPERIDINE 1 benzyl 4 4 4 5 5 tetramethyl 1 3 2 dioxaborolan 2 yl 1 2 3 6 tetrahydropyridine 2 9 DIAZASPIRO 5 5 UNDECAN 1 ONE HYDROCHLORIDE 1 benzyloxycarbonyl 5 methoxycarbonyl piperidine 3 carboxylic acid 3 ETHOXYCARBONYLMETHYL 8 AZA BICYCLO 3 2 1 OCTANE 8 CARBOXYLIC ACID TERT BUTYL ESTER 2 benzyl 2 aza bicyclo 2 2 1 hept 5 ene 1 2 hydroxy 3 4 dimethoxyphenyl ethanone 1 BOC 4 4 BROMOPHENYL 4 PIPERIDINECARBOXYLIC ACID 9 Boc 2 9 DIAZASPIRO 5 5 UNDECAN 1 ONE 2 benzyl 8 Boc 2 8 diaza spiro 5 5 undecan 1 one 2 4 Dimethylphenylhydrazine HCl salt 12 phenyldodecanoic acid 11 phenylundecanoic acid 2 aminoisoindoline 1 3 dione hydrochloride 10 phenyldecanoic acid 1 2 hydroxy 4 5 dimethylphenyl ethanone 4 1 2 3 4 tetrahydronaphthalen 1 yl phenol 1 2 bis bromomethyl 3 nitrobenzene 3 propylbenzenamine 7 amino 8 nitro 2 phenyl 4H chromen 4 one 2 Azaspiro 3 3 heptane 6 carboxylic acid trifluoroacetate 3 1 ADAMANTYL PENTANE 2 4 DIONE

4 6 HYDROXY 7 TRICYCLO 3 3 1 13 7 DEC 1 YL 2 NAPHTHALENYL BENZOIC ACID 3 ADAMANTAN 1 YLBENZOIC ACID 1 1 ADAMANTYL METHANAMINE HYDROCHLORIDE 2 1 ADAMANTYL N HYDROXYACETAMIDE 1 ADAMANTANECARBALDEHYDE THIOSEMICARBAZONE 3 1 ADAMANTYL PROPANOIC ACID 4 OXOADAMANTANE 1 CARBOXAMIDE 1 1 ADAMANTYL PROPAN 1 ONE 1 2 METHYLAMINOPROPYL ADAMANTANE HYDROCHLORIDE 1 ADAMANTAN 1 YL PROPAN 2 ONE 5 MORPHOLIN 4 YLCARBONYL ADAMANTAN 2 ONE 4 1 ADAMANTYL CYCLOHEXANOL 4 ADAMANTAN 1 YLMETHYL THIAZOL 2 YLAMINE 2 ADAMANTAN 1 YL 1 PHENYL ETHANONE 1 1 ADAMANTYL 2 BROMOPROPAN 1 ONE 1 METHYLDIAMANTANE 1 adamanTYLMETHYL NICOTINATE 4 ADAMANTAN 1 YL 5 METHYL THIAZOL 2 YLAMINE 1 2 DIMETHYLAMINOPROPYL ADAMANTANE HYDROCHLORIDE 1 2 METHYLAMINOPROPYL 2 PHENYLADAMANTANE HYDROCHLORIDE 1 1 ADAMANTYLCARBONYL PIPERAZINE 1 1 ADAMANTYLMETHYL PIPERAZINE 1 3 AMINOPROPYL ADAMANTANE HYDROCHLORIDE 1 3 METHYLAMINOBUTYL ADAMANTANE HYDROCHLORIDE 3 ADAMANTAN 1 YL 6 7 8 9 TETRAHYDRO 5H 1 2 4 TRIAZOLO 4 3 A AZEPINE 3 ADAMANTANECARBOXYLIC ACID PHENYL ESTER 3 2 1 ADAMANTYL ETHYL 2 4 IMIDAZOLIDINEDIONE 1 ADAMANTYLACETYLENE 1 1 ADAMANTYL 2 PROPYLAMINO ETHANONE 4 1 ADAMANTYL 2 METHYLPHENOL