3 CYANOPYRIDINE 4 BORONIC ACID PINACOL ESTER 3 CHLORO 4 5 5 DIMETHYL 1 3 2 DIOXABORINAN 2 YL PYRIDINE 2 Thiophen 2 yl morpholine 2 Furan 2 yl morpholine 3 Furan 3 yl morpholine 2 PYRIDINECARBOXAMIDE N 2 CHLORO 4 PYRIDINYL 6 METHYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 2 3 Furanyl morpholine 3 CHLORO 2 4 MORPHOLINO PYRIDINE 4 BORONIC ACID PINACOL ESTER 2 Cyclohexylmethyl morpholine 3 CHLORO 2 MORPHOLINOPYRIDINE 4 BORONIC ACID 5 6 7 8 tetrahydroimidazo 1 2 a pyrazine 2 carboxylic acid 2 Cyclopropylmethyl morpholine 1 ETHYL 4 TERT BUTYLOXYCARBONYL PIPERAZIN 2 ONE 2 Cyclopentylmethyl morpholine 3 Cyclopropylmethyl morpholine 2 2 Oxetanyl morpholine 2 Oxetan 3 yl morpholine 3 Cyclopentylmorpholine 2 METHYL 3 OXOPIPERAZINE HYDROCHLORIDE 4 4 Difluoro L prolinamide hydrochloride 1S tert butyl 6 oxo 5 oxa 2 aza bicyclo 2 2 1 heptane 2 carboxylate 3aR 6aS octahydrocyclopenta c pyrrole 1 benzyl 3 methylpyrrolidin 3 ol 2 Cyclohexyl morpholine 3 ACETAMIDOPYRROLIDINE 2 Tetrahydro 3 furanyl morpholine 3 4 Pyridinyl morpholine 2 4 Pyridinyl morpholine 4 1 Piperazinylmethyl benzoicacid 1 tert butyl 2 methyl 2 ethyl 4 oxopyrrolidine 1 2 dicarboxylate

3 Azaspiro 5 5 undecan 9 one 4 Amino 3 Pyrrolidinol 3 methylpyrrolidin 3 ol hydrochloride 3 Azabicyclo 3 1 0 hexane 7 Azaspiro 3 5 nonane 7 3 TRIFLUOROMETHYL PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 Bromo 1 2 3 4 tetrahydro 1 7 naphthyridine 3 2 Bromoethyl Pyridine 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 2 AMINE 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 3 Hydroxymethylmorpholine 7 Chloro 3 quinolinamine 6 2 CARBOXYBIPHENYL 4 YL METHYL 7 HYDROXY 5 PROPYLPYRAZOLO 1 5 A PYRIMIDINE 2 Amino N cyclopropyl acetamide 1 2 4 CHLOROPHENYL 7 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ETHAN 1 ONE 2 TERT BUTYL 7 CHLORO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 5 7 BIS TRIFLUOROMETHYL 2 METHYLTHIO PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 2 3 DIAMINE 5 Maleimidovaleric acid hydrazide 5 7 BIS TRIFLUOROMETHYL 3 CYANOPYRAZOLO 1 5 A PYRIMIDINE 3 Maleimidopropionicacidhydrazide 6 4 METHOXY PHENYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 2 Maleimidoacetic acid hydrazide 6 Maleimidocaproic acid hydrazide Trifluoroacetic Acid 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 2 Ethyl morpholine 6 BROMO PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 7 AMINO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 Isobutylmorpholine 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE

2 4 BROMOPHENYL 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 BROMO 3 CHLOROPYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 7 Methyl 5 azaspiro 2 4 heptan 7 amine 5 1 METHYL CYCLOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 ISOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 Azaspiro 2 4 heptan 1 amine dihydrochloride 9CI 6 TERT BUTYLSULFONYL 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 5 METHYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 YL HYDRAZINE 2R 6R 2 6 Dimethyl piperazine 6 NITROPYRAZOLO 1 5 A PYRIMIDINE 5 Azaspiro 2 4 hept 1 yl carbamic acid tert butyl ester 7 CHLORO 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 METHYLPYRAZOLO 1 5 A PYRIMIDINE 1 4 Diazabicyclo 3 2 2 nonane dihydrochloride 3 Methyl 3 azetidinecarbonitrile hydrochloride 2 5 7 TRIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 METHYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 6 Oxa 3 aza bicyclo 3 1 1 heptane 2 4 Bromophenyl morpholine 2 TERT BUTYL 7 HYDRAZINO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 Bromo quinolin 2 ylamine 2 TERT BUTYL 7 CHLORO 3 IODO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE 2 Hydrazinyl 6 methylpyridine 7 PYRIDIN 3 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2R 6R 2 6 Dimethyl piperazine 2HCl 2 METHOXYMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2R 6R 2 6 Diethyl piperazine 5 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID

7 METHOXY 2 5 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 3 Bis benzyl amino hexahydro 2H azepin 2 one 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 5 OL 4 4 Boc piperazin 1 yl 3 trifluoromethylaniline 6 METHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 4 Benzylmorpholin 2 yl methylamine 7 FURAN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2S 6S 2 6 Dimethylmorpholine 4 2 PHENYL 5 7 BIS TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDIN 3 YL PHENOL 3 2 4 DIMETHYLAMINO PHENYL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 1 2 3 5 6 7 HEXAHYDRO 4 8A 9 TRIAZA CYCLOPENTA A S INDACEN 8 YLAMINE 3 3 4 DIETHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 6 4 METHOXY PHENYL 3 THIOPHEN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 2 Piperazin 1 yl benzoic acid methyl ester 7 AMINOPYRAZOLO 1 5 A PYRIMIDINE 6 CARBONITRILE 4 7 Diaza spiro 2 5 octane 4 carboxylic acid tert butyl ester 5 METHYL 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 OL 6 BROMO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 2R 3 4 Dihydro 2H 1 benzopyrane 2 methylamine hydrochloride 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIOL 3 4 Boc piperazin 1 yl aniline 5 7 DICHLORO 3 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 4 FLUOROPHENYL 2 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 3 Isopropylmorpholine 1 quinolin 2 yl ethanone 3 Ethylmorpholine 2 Methyl 1 5 pentanediol 5 Hydroxymethyl dihydrofuran 2 3H one 2 4 chlorophenylamino 4 9 dioxo 4 9 dihydronaphtho 2 3 b thiophene 3 carboxylic acid 4 bromo 2 methoxythiazole