1 tert butyl 4 ethyl 4 methyl 3 oxopiperidine 1 4 dicarboxylate 4 bromo 1 propyl 1 2 3 6 tetrahydropyridine hydrochloride 6 BROMO 2 CHLORO 3 METHYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL PYRIDINE 2 6 DICHLORO 3 METHYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL PYRIDINE 2 3 DIMETHOXYPYRIDINE 4 BORONIC ACID 3 FLUOROPYRIDINE 4 BORONIC ACID HYDRATE 3 5 DIMETHYLPYRIDINE 4 BORONIC ACID PINACOL ESTER 3 BROMO 2 METHOXYPYRIDINE 4 BORONIC ACID 2 ETHOXYPYRIDINE 4 BORONIC ACID 3 FLUORO 5 METHYLPYRIDINE 4 BORONIC ACID 3 PICOLINE 4 BORONIC ACID HCL 3 CHLORO 2 METHOXYPYRIDINE 4 BORONIC ACID PINACOL ESTER 5 BROMO 2 ETHOXYPYRIDINE 4 BORONIC ACID 3 BROMO 5 METHOXY 4 PYRIDINYL BORONIC ACID 5 pentylpicolinic acid 3 BROMO 2 FLUOROPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 3 FLUOROPHENYL PYRIDINE 4 BORONIC ACID PINACOL ESTER 2 ETHOXYCARBONYL PYRIDIN 4 YL BORONIC ACID 2 FLUORO 5 METHYLPYRIDINE 4 BORONIC ACID PINACOL ESTER 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 2 6 PYRIDINEDICARBOXYLIC ACID 2 6 DIMETHYL ESTER 2 PICOLINE 4 BORONIC ACID HCL 2 AMINO 4 PYRIDYL BORONIC ACID 3 CYANOPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 CHLORO 3 CYANOPYRIDINE 4 BORONIC ACID 3 CYANOPYRIDINE 4 BORONIC ACID 2 PYRIDINECARBOXAMIDE N 2 CHLORO 4 PYRIDINYL 6 METHYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 3 CHLORO 4 5 5 DIMETHYL 1 3 2 DIOXABORINAN 2 YL PYRIDINE 3 CHLORO 2 MORPHOLINOPYRIDINE 4 BORONIC ACID 3 CHLORO 2 4 MORPHOLINO PYRIDINE 4 BORONIC ACID PINACOL ESTER 1 ETHYL 4 TERT BUTYLOXYCARBONYL PIPERAZIN 2 ONE

5 6 7 8 tetrahydroimidazo 1 2 a pyrazine 2 carboxylic acid 2 METHYL 3 OXOPIPERAZINE HYDROCHLORIDE 4 4 Difluoro L prolinamide hydrochloride 1 benzyl 3 methylpyrrolidin 3 ol 3 ACETAMIDOPYRROLIDINE 1S tert butyl 6 oxo 5 oxa 2 aza bicyclo 2 2 1 heptane 2 carboxylate 1 tert butyl 2 methyl 2 ethyl 4 oxopyrrolidine 1 2 dicarboxylate 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 2 AMINE 7 3 TRIFLUOROMETHYL PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 3 methylpyrrolidin 3 ol hydrochloride 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 6 2 CARBOXYBIPHENYL 4 YL METHYL 7 HYDROXY 5 PROPYLPYRAZOLO 1 5 A PYRIMIDINE 1 2 4 CHLOROPHENYL 7 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ETHAN 1 ONE 5 7 BIS TRIFLUOROMETHYL 2 METHYLTHIO PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 7 BIS TRIFLUOROMETHYL 3 CYANOPYRAZOLO 1 5 A PYRIMIDINE 2 TERT BUTYL 7 CHLORO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 6 4 METHOXY PHENYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 2 3 DIAMINE 7 AMINO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 6 BROMO PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 2 4 BROMOPHENYL 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 5 1 METHYL CYCLOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 6 BROMO 3 CHLOROPYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 ISOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 6 TERT BUTYLSULFONYL 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 6 NITROPYRAZOLO 1 5 A PYRIMIDINE 5 METHYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 YL HYDRAZINE 6 METHYLPYRAZOLO 1 5 A PYRIMIDINE

7 CHLORO 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE 2 TERT BUTYL 7 CHLORO 3 IODO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 METHOXYMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 5 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 METHOXY 2 5 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 5 7 TRIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 METHYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 TERT BUTYL 7 HYDRAZINO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 7 PYRIDIN 3 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 5 OL 4 2 PHENYL 5 7 BIS TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDIN 3 YL PHENOL 7 FURAN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 6 METHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 1 2 3 5 6 7 HEXAHYDRO 4 8A 9 TRIAZA CYCLOPENTA A S INDACEN 8 YLAMINE 3 2 4 DIMETHYLAMINO PHENYL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 6 4 METHOXY PHENYL 3 THIOPHEN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 3 4 DIETHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 5 METHYL 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 OL 7 AMINOPYRAZOLO 1 5 A PYRIMIDINE 6 CARBONITRILE 1 quinolin 2 yl ethanone 3 4 FLUOROPHENYL 2 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 5 7 DICHLORO 3 METHYLPYRAZOLO 1 5 A PYRIMIDINE 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIOL 6 BROMO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 4 bromo 2 methoxythiazole 5 bromo 2 methoxythiazole 2 2 2 diethoxyethoxy 1 1 diethoxyethane 2 chloro N 2 chloroethyl N cyclopropylmethyl ethanamine hydrochloride

6E 10E tricosa 6 10 dien 1 ol 6 hydroxy 9H purine 3 N oxide 1R 4aR 4bS 10aR methyl 2 4b 8 8 10a pentamethyl 1 4 4a 4b 5 6 7 8 8a 9 10 10a dodecahydrophenanthrene 1 carboxylate 2 4 chlorophenylamino 4 9 dioxo 4 9 dihydronaphtho 2 3 b thiophene 3 carboxylic acid 4 bromo 2 isopropylthiazole 5 6 7 trimethoxy 2 phenylquinolin 4 1H one 2 2 4 dimethylphenyl 1 2 dihydropyrazol 3 one 3 4 4 5 5 tetramethyl 1 3 2 dioxaborolan 2 yl cyclopentanone 2 aminobenzoic 3 4 dimethoxybenzoic anhydride 4 4 1E 1 E 2 2 1 phenyl 1H pyrazole 3 5 diyl bis ethene 2 1 diyl bis 2 methoxyphenol 2 2 4 dimethylphenyl phthalazin 1 2H one 1 2 4 dimethylphenyl 2 3 methoxyphenyl diazene 1 benzhydrylamino 3 chloropropan 2 ol 1 8 diazaspiro 5 5 undecan 7 one 1 benzhydryl 3 3 difluoroazetidine 1 oxa 3 9 diazaspiro 5 5 undecan 2 one hydrochloride 8 methoxycarbonyl octanoic acid 1 Propanone 1 2 4 difluorophenyl 2 hydroxy 2R 2 methylpiperidine 2 carboxylic acid hydrochloride 2 OXA SPIRO 3 3 HEPTAN 6 ONE 2R 4S 1 tert Butoxycarbonyl 4 fluoropyrrolidine 2 carboxylic acid 3 fluorotetrahydro 2H pyran 4 yl methanesulfonate 1 bromomethyl 2 trifluoromethyl 4 methylsulfonyl benzene 4 methylsulfonyl 2 trifluoromethyl benzaldehyde 4 2 Oxo 2 2 oxo 4 R phenyl oxazolidin 3 yl ethyl piperidine 1 carboxylic acid tert butyl ester 2 1 ADAMANTANYL ETHYL ACETATE 4 4 difluoro N S 3 1S 3R 5R 2 fluoro 3 3 isopropyl 5 methyl 4H 1 2 4 triazol 4 yl 8 aza bicyclo 3 2 1 octan 8 yl 1 phenylpropyl adamantanecarboxamide 3 3 difluoro N S 3 1S 3R 5R 3 3 isopropyl 5 methyl 4H 1 2 4 triazol 4 yl 8 aza bicyclo 3 2 1 octan 8 yl 1 phenylpropyl piperidine 4 carboxamide 5 hydroxy 5 trifluoromethyl dihydrofuran 2 3H one 1 6 Trifluoromethyl pyridin 3 yl ethanone