2 Oxa 7 azaspiro 4 5 decane 2 Oxa 8 azaspiro 4 5 decane 5 BROMO 2 ETHOXYPYRIDINE 4 BORONIC ACID 1 4 Diazabicyclo 3 2 2 nonane 2 3 FLUOROPHENYL PYRIDINE 4 BORONIC ACID PINACOL ESTER 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 2 6 PYRIDINEDICARBOXYLIC ACID 2 6 DIMETHYL ESTER 2 FLUORO 5 METHYLPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 PICOLINE 4 BORONIC ACID HCL 2 ETHOXYCARBONYL PYRIDIN 4 YL BORONIC ACID 2 3 pyridinyl morpholine 3 CYANOPYRIDINE 4 BORONIC ACID 2 CHLORO 3 CYANOPYRIDINE 4 BORONIC ACID 3 CYANOPYRIDINE 4 BORONIC ACID PINACOL ESTER 3 3 Pyridinyl morpholine 2 Thiophen 2 yl morpholine 2 AMINO 4 PYRIDYL BORONIC ACID 2 Furan 2 yl morpholine 3 CHLORO 4 5 5 DIMETHYL 1 3 2 DIOXABORINAN 2 YL PYRIDINE 3 Furan 3 yl morpholine 5 6 7 8 tetrahydroimidazo 1 2 a pyrazine 2 carboxylic acid 2 Cyclopropylmethyl morpholine 1 ETHYL 4 TERT BUTYLOXYCARBONYL PIPERAZIN 2 ONE 2 Cyclopentylmethyl morpholine 3 CHLORO 2 4 MORPHOLINO PYRIDINE 4 BORONIC ACID PINACOL ESTER 2 Cyclohexylmethyl morpholine 3 CHLORO 2 MORPHOLINOPYRIDINE 4 BORONIC ACID 2 PYRIDINECARBOXAMIDE N 2 CHLORO 4 PYRIDINYL 6 METHYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 2 3 Furanyl morpholine 2 METHYL 3 OXOPIPERAZINE HYDROCHLORIDE 2 2 Oxetanyl morpholine

3 Cyclopropylmethyl morpholine 3 Cyclopentylmorpholine 4 4 Difluoro L prolinamide hydrochloride 2 Oxetan 3 yl morpholine 2 Cyclohexyl morpholine 3 ACETAMIDOPYRROLIDINE 2 Tetrahydro 3 furanyl morpholine 2 4 Pyridinyl morpholine 3 4 Pyridinyl morpholine 1 benzyl 3 methylpyrrolidin 3 ol 3aR 6aS octahydrocyclopenta c pyrrole 1S tert butyl 6 oxo 5 oxa 2 aza bicyclo 2 2 1 heptane 2 carboxylate 4 1 Piperazinylmethyl benzoicacid 1 tert butyl 2 methyl 2 ethyl 4 oxopyrrolidine 1 2 dicarboxylate 3 Azaspiro 5 5 undecan 9 one 4 Amino 3 Pyrrolidinol 3 methylpyrrolidin 3 ol hydrochloride 7 Azaspiro 3 5 nonane 3 Azabicyclo 3 1 0 hexane 7 3 TRIFLUOROMETHYL PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 Bromo 1 2 3 4 tetrahydro 1 7 naphthyridine 3 2 Bromoethyl Pyridine 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 2 AMINE 3 Hydroxymethylmorpholine 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 6 2 CARBOXYBIPHENYL 4 YL METHYL 7 HYDROXY 5 PROPYLPYRAZOLO 1 5 A PYRIMIDINE 7 Chloro 3 quinolinamine 1 2 4 CHLOROPHENYL 7 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ETHAN 1 ONE 2 Amino N cyclopropyl acetamide 5 7 BIS TRIFLUOROMETHYL 2 METHYLTHIO PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE

2 TERT BUTYL 7 CHLORO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 5 Maleimidovaleric acid hydrazide 3 Maleimidopropionicacidhydrazide 5 7 BIS TRIFLUOROMETHYL 3 CYANOPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 2 3 DIAMINE 6 4 METHOXY PHENYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 2 Maleimidoacetic acid hydrazide 6 Maleimidocaproic acid hydrazide Trifluoroacetic Acid 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 2 Ethyl morpholine 2 Isobutylmorpholine 7 AMINO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2 4 BROMOPHENYL 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 BROMO PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 7 Methyl 5 azaspiro 2 4 heptan 7 amine 5 1 METHYL CYCLOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 ISOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 Azaspiro 2 4 heptan 1 amine dihydrochloride 9CI 6 BROMO 3 CHLOROPYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 6 TERT BUTYLSULFONYL 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 5 Azaspiro 2 4 hept 1 yl carbamic acid tert butyl ester 6 NITROPYRAZOLO 1 5 A PYRIMIDINE 2R 6R 2 6 Dimethyl piperazine 5 METHYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 YL HYDRAZINE 7 CHLORO 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 1 4 Diazabicyclo 3 2 2 nonane dihydrochloride 6 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 Methyl 3 azetidinecarbonitrile hydrochloride 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE

6 Oxa 3 aza bicyclo 3 1 1 heptane 2 4 Bromophenyl morpholine 2 TERT BUTYL 7 HYDRAZINO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 Bromo quinolin 2 ylamine 2 TERT BUTYL 7 CHLORO 3 IODO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 METHYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 METHOXY 2 5 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 5 7 TRIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2R 6R 2 6 Diethyl piperazine 5 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 METHOXYMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 5 OL 3 Bis benzyl amino hexahydro 2H azepin 2 one 2 Hydrazinyl 6 methylpyridine 7 PYRIDIN 3 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2R 6R 2 6 Dimethyl piperazine 2HCl 4 Benzylmorpholin 2 yl methylamine 4 2 PHENYL 5 7 BIS TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDIN 3 YL PHENOL 2S 6S 2 6 Dimethylmorpholine 7 FURAN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 7 AMINOPYRAZOLO 1 5 A PYRIMIDINE 6 CARBONITRILE 3 2 4 DIMETHYLAMINO PHENYL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 2 Piperazin 1 yl benzoic acid methyl ester 6 4 METHOXY PHENYL 3 THIOPHEN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 6 METHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 4 4 Boc piperazin 1 yl 3 trifluoromethylaniline 1 2 3 5 6 7 HEXAHYDRO 4 8A 9 TRIAZA CYCLOPENTA A S INDACEN 8 YLAMINE 3 3 4 DIETHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 4 7 Diaza spiro 2 5 octane 4 carboxylic acid tert butyl ester