5 tert butyl 3a ethyl hexahydro 1H pyrrolo 3 2 c pyridine 3a 5 6H dicarboxylate 4 4 bromophenyl piperidine 4 carbonitrile hydrochloride 1 methyl 4 phenylpiperidine 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 3 PYRIDINAMINE 2 TRIFLUOROMETHYL PYRIDINE 4 BORONIC ACID PINACOL ESTER 3 METHYLPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 CHLORO 3 METHYLPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 CHLORO 3 METHYL 5 PHENYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL PYRIDINE 2 CHLORO 5 METHOXYPYRIDINE 4 BORONIC ACID 2 CHLORO 3 FLUORO 5 PICOLINE 4 BORONIC ACID 5 BROMO 2 TRIFLUOROMETHYL PYRIDIN 4 YLBORONIC ACID 2 CARBOXYPYRIDINE 4 BORONIC ACID 2 TRIFLUOROMETHYL PYRIDINE 4 BORONIC ACID 2 N BOC AMINO 6 ETHOXYCARBONYL 4 PYRIDINE BORONIC ACID PINACOL ESTER 4 BORONO 2 6 PYRIDINEDICARBOXYLIC ACID 2 6 DIETHYL ESTE 2 CHLORO 3 FLUOROPYRIDINE 4 BORONIC ACID 5 hexylpicolinic acid 2 6 DIMETHYL PYRIDINE 4 BORONIC ACID 5 BROMO 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 2 PYRIDINECARBONITRILE 2 CHLORO 3 CYANOPYRIDINE 4 BORONIC ACID PINACOL ESTER 2 HYDROXY PYRIDINE 4 BORONIC ACID 2 TERT BUTYLDIMETHYLSILYLOXY METHYL PYRIDINE 4 BORONIC ACID PINACOL ESTER 2 CYANOPYRIDIN 4 YL BORONIC ACID 3 FLUORO 2 4 MORPHOLINO PYRIDINE 4 BORONIC ACID PINACOL ESTER 2 PYRIDINECARBOXAMIDE 6 METHYL N 4 METHYL 2 THIAZOLYL 4 4 4 5 5 TETRAMETHYL 1 3 2 DIOXABOROLAN 2 YL 1 3 DIHYDRO 1 HYDROXY 1 2 OXABOROLO 4 3 C PYRIDINE 1 BENZYL 4 3 NITROPYRIDIN 2 YL PIPERAZINE 1 BOC 4 BUTYLPIPERAZINE 1 Boc 4 3 NITRO PYRIDIN 2 YL PIPERAZINE 1 ISOPROPYLPIPERAZINE

1 BOC 4 ISOPROPYLPIPERAZINE 3 benzyl 7 tert butyl 9 oxo 3 7 diaza bicyclo 3 3 1 nonane 3 7 dicarboxylate 2 4 tert butoxycarbonyl 2 methylpiperazin 1 yl acetic acid 4 BENZYL 3 OXOPIPERAZINE 1 CARBOXYLIC ACID TERT BUTYL ESTER 2 CARBOXYMETHYL 3 OXO PIPERAZINE 1 CARBOXYLIC ACID TERT BUTYL ESTER 4 benzylpiperazin 1 amine 1 1 9H fluoren 9 yl methoxy carbonyl pyrrolidine 2 carbonyl pyrrolidine 2 carboxylic acid 1 benzyl 3 methylpyrrolidin 3 amine 1 tert butyl 2 methyl 2 3 chloropropyl pyrrolidine 1 2 dicarboxylate 1 benzylpyrrolidine 3 carbonitrile oxalate 1 1 ADAMANTYLCARBONYL PYRROLIDINE 2 CARBOXYLIC ACID 5 hydroxymethyl 1 methylpyrrolidin 2 one 1 tert butyl 3 ethyl 3 methyl 4 oxopyrrolidine 1 3 dicarboxylate 3 benzyl 6 oxa 3 aza bicyclo 3 1 0 hexane 3 pyridin 4 yl 1H pyrazol 5 amine 3 CHLORO 6 METHYLPYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 2 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 5 CARBOXYLIC ACID 1 2 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ETHAN 1 ONE 4 7 HYDROXY 5 PROPYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL METHYL 1 1 BIPHENYL 2 CARBOXAMIDE 7 CHLORO 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 5 BUTYL 6 2 1H TETRAZOL 5 YL 1 1 BIPHENYL 4 YL METHYL PYRAZOLO 1 5 A PYRIMIDIN 7 OL 5 7 BIS TRIFLUOROMETHYL 3 CYANO 2 METHYLTHIO PYRAZOLO 1 5 A PYRIMIDINE 4 2 5 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 7 YL AMINO 4 OXOBUTANOIC ACI D 6 BROMO PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 7 2 PYRIDINYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 2 OL 6 4 METHOXY PHENYL 3 PYRIDIN 3 YL PYRAZOLO 1 5 A PYRIMIDINE 1 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 2 ONE 2 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 5 DIMETHYL 6 PHENYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE

5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 5 CYCLOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 9 TRIFLUOROMETHYL 5 6 7 8 TETRAHYDRO PYRAZOLO 5 1 B QUINAZOLINE 2 CARBOXYLIC ACID 3 BROMO 7 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 BROMO 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 2 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 5 7 DIOL 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 5 IODOPYRAZOLO 1 5 A PYRIMIDINE 3 BROMO 2 TERT BUTYL 7 CHLORO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 7 METHOXY 5 METHYL 2 PHENYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 HYDROXYMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 5 7 DICHLORO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 7 CHLORO 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 6 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 2 7 DIMETHYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 6 ACETYL 7 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 NITROPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 4 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDIN 2 YL PHENYL DIMETHYL AMINE 2 2 METHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 THIOPHEN 2 YL 6 3 4 5 TRIMETHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 2 3 METHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 3 THIOPHEN 2 YL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 3 2 2 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 3 PHENYL 6 3 4 5 TRIMETHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 3 CHLOROPHENYL 2 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 3 METHYLPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIOL 2 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ACETIC ACID 5 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 7 HYDROXY 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE

6 4 METHOXY PHENYL 2 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 2 3 BROMO PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 6 methylmorpholin 3 one 2 METHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 3 4 METHOXYPHENYL 2 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 methylmorpholin 3 one 5 6 DIHYDRO 4 METHOXY 2H PYRAN 5 S 5 methyl 2 phenylthio dihydrofuran 2 3H one 7 methoxy 7 oxoheptanoic acid 1 3 tert butyl 5 iodo 4 methoxyphenyl pyrimidine 2 4 1H 3H dione 1 2 4 dimethylphenyl 3 phenyl 1H pyrazole 5 4H one 3 3 4 dimethoxyphenyl 1 2 hydroxy 3 methylphenyl prop 2 en 1 one 2 3 4 dimethoxyphenyl 3 hydroxy 8 methyl 4H chromen 4 one 2 3 4 dimethoxyphenyl 3 hydroxyquinolin 4 2H one 4 4 1E 1 E 2 2 1 phenyl 1H pyrazole 3 5 diyl bis ethene 2 1 diyl diphenol 4 4 methoxyquinolin 2 yl benzene 1 2 diol 2 3 4 dihydroxyphenyl 6 ethyl 3 hydroxy 4H chromen 4 one 2 3 4 dimethoxyphenyl 3 hydroxy 7 methoxyquinolin 4 1H one 1 2 4 dimethylphenyl 3 3 methoxyphenyl 1H pyrazol 5 4H one 1 benzyl 3 3 difluoropiperidin 4 one hydrochloride 3 TRIFLUOROMETHOXY PIPERIDINE 3 Fluoro 2 iodoaniline 2R 4S 1 benzyl 2 Methyl 4 hydroxypyrrolidine 1 2 dicarboxylate 2S 4R 1 benzyl 2 Methyl 4 hydroxypyrrolidine 1 2 dicarboxylate 4 1 Methylpiperidin 4 yl oxy aniline 3 Ethynyl 5 trifluoromethyl pyridine 2 2 2 Trifluoro 1 3 methoxypyridin 4 yl ethanone 2 trifluoromethyl 4 methylsulfonyl phenyl methanol 2 4 6 fluoroquinolin 4 yl cyclohexyl acetic acid 2 1 tert butoxycarbonyl piperidin 4 yl 2 methylpropanoic acid