4 1 Piperazinylmethyl benzoicacid 1 tert butyl 2 methyl 2 ethyl 4 oxopyrrolidine 1 2 dicarboxylate 3 Azaspiro 5 5 undecan 9 one 4 Amino 3 Pyrrolidinol 3 methylpyrrolidin 3 ol hydrochloride 7 Azaspiro 3 5 nonane 3 Azabicyclo 3 1 0 hexane 7 3 TRIFLUOROMETHYL PHENYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 Bromo 1 2 3 4 tetrahydro 1 7 naphthyridine 3 2 Bromoethyl Pyridine 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 OL 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDIN 2 AMINE 7 Chloro 3 quinolinamine 3 Hydroxymethylmorpholine 6 2 CARBOXYBIPHENYL 4 YL METHYL 7 HYDROXY 5 PROPYLPYRAZOLO 1 5 A PYRIMIDINE 1 2 4 CHLOROPHENYL 7 METHYLPYRAZOLO 1 5 A PYRIMIDIN 6 YL ETHAN 1 ONE 2 Amino N cyclopropyl acetamide 5 7 BIS TRIFLUOROMETHYL 2 METHYLTHIO PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXAMIDE 5 7 BIS TRIFLUOROMETHYL 3 CYANOPYRAZOLO 1 5 A PYRIMIDINE 3 Maleimidopropionicacidhydrazide 2 TERT BUTYL 7 CHLORO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 4 METHOXY PHENYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 2 3 DIAMINE 5 Maleimidovaleric acid hydrazide 5 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 2 Ethyl morpholine 6 Maleimidocaproic acid hydrazide Trifluoroacetic Acid 2 Maleimidoacetic acid hydrazide 7 AMINO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 Isobutylmorpholine

6 BROMO PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 Azaspiro 2 4 heptan 1 amine dihydrochloride 9CI 5 ISOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 5 1 METHYL CYCLOPROPYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 7 Methyl 5 azaspiro 2 4 heptan 7 amine 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2 4 BROMOPHENYL 5 7 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 BROMO 3 CHLOROPYRAZOLO 1 5 A PYRIMIDINE 2 CARBOXYLIC ACID 6 TERT BUTYLSULFONYL 2 METHYLPYRAZOLO 1 5 A PYRIMIDIN 7 AMINE 5 Azaspiro 2 4 hept 1 yl carbamic acid tert butyl ester 5 METHYL 3 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 YL HYDRAZINE 2R 6R 2 6 Dimethyl piperazine 6 NITROPYRAZOLO 1 5 A PYRIMIDINE 1 4 Diazabicyclo 3 2 2 nonane dihydrochloride 7 CHLORO 5 6 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 3 Methyl 3 azetidinecarbonitrile hydrochloride 6 METHYLPYRAZOLO 1 5 A PYRIMIDINE 5 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 Bromo quinolin 2 ylamine 2 TERT BUTYL 7 CHLORO 3 IODO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 2 4 Bromophenyl morpholine 2 TERT BUTYL 7 HYDRAZINO 5 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 Oxa 3 aza bicyclo 3 1 1 heptane 2 METHYL 7 TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 5 7 TRIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 7 METHOXY 2 5 DIMETHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 5 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2R 6R 2 6 Diethyl piperazine 7 HYDROXY 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 2 METHOXYMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID

2R 6R 2 6 Dimethyl piperazine 2HCl 7 PYRIDIN 3 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 5 OL 4 2 PHENYL 5 7 BIS TRIFLUOROMETHYL PYRAZOLO 1 5 A PYRIMIDIN 3 YL PHENOL 2 Hydrazinyl 6 methylpyridine 3 Bis benzyl amino hexahydro 2H azepin 2 one 6 METHYL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBOXYLIC ACID 4 Benzylmorpholin 2 yl methylamine 7 FURAN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 CARBONITRILE 2S 6S 2 6 Dimethylmorpholine 4 4 Boc piperazin 1 yl 3 trifluoromethylaniline 1 2 3 5 6 7 HEXAHYDRO 4 8A 9 TRIAZA CYCLOPENTA A S INDACEN 8 YLAMINE 3 2 4 DIMETHYLAMINO PHENYL PYRAZOLO 1 5 A PYRIMIDIN 6 YL PROPAN 1 OL 2 Piperazin 1 yl benzoic acid methyl ester 6 4 METHOXY PHENYL 3 THIOPHEN 2 YL PYRAZOLO 1 5 A PYRIMIDINE 3 3 4 DIETHOXY PHENYL 6 4 METHOXY PHENYL PYRAZOLO 1 5 A PYRIMIDINE 7 AMINOPYRAZOLO 1 5 A PYRIMIDINE 6 CARBONITRILE 4 7 Diaza spiro 2 5 octane 4 carboxylic acid tert butyl ester 5 METHYL 2 PHENYL PYRAZOLO 1 5 A PYRIMIDIN 7 OL 2R 3 4 Dihydro 2H 1 benzopyrane 2 methylamine hydrochloride 5 7 DICHLORO 3 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 4 Boc piperazin 1 yl aniline 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 5 7 DIOL 6 BROMO 2 METHYLPYRAZOLO 1 5 A PYRIMIDINE 3 Isopropylmorpholine 3 4 FLUOROPHENYL 2 7 DIMETHYL PYRAZOLO 1 5 A PYRIMIDINE 6 CARBOXYLIC ACID 3 Ethylmorpholine 1 quinolin 2 yl ethanone 1R 4aR 4bS 10aR methyl 2 4b 8 8 10a pentamethyl 1 4 4a 4b 5 6 7 8 8a 9 10 10a dodecahydrophenanthrene 1 carboxylate 2 4 chlorophenylamino 4 9 dioxo 4 9 dihydronaphtho 2 3 b thiophene 3 carboxylic acid

5 Hydroxymethyl dihydrofuran 2 3H one 4 bromo 2 isopropylthiazole 2 Methyl 1 5 pentanediol 4 bromo 2 methoxythiazole 10H Phenoxazine 10 ethanol 5 bromo 2 methoxythiazole 3 3 5 Di tert butyl 4 hydroxy phenyl 2 2 dimethylpropanol 6 hydroxy 9H purine 3 N oxide 8 Methyl 8 azabicyclo 3 3 1 oct 6 en 3 ol HCl 6E 10E tricosa 6 10 dien 1 ol 2 chloro N 2 chloroethyl N cyclopropylmethyl ethanamine hydrochloride 1R 5S tert Butyl 3 trifluoromethylsulfonyloxy 8 azabicyclo 3 2 1 oct 2 ene 8 carboxylate 4R 1 Boc 4 hydroxy azepane 4S 1 Boc 4 hydroxy azepane 2 2 2 diethoxyethoxy 1 1 diethoxyethane 1 1 Bis hydroxymethyl cyclopropane 1S 2R 1 Phenyl 2 1 pyrrolidinyl 1 propanol 3 4 4 5 5 tetramethyl 1 3 2 dioxaborolan 2 yl cyclopentanone 2 2 4 dimethylphenyl 1 2 dihydropyrazol 3 one 5 6 7 trimethoxy 2 phenylquinolin 4 1H one 5 Hydroxymethyl morpholin 3 one 2 aminobenzoic 3 4 dimethoxybenzoic anhydride 2 2 4 dimethylphenyl phthalazin 1 2H one 4 1 Amino ethyl benzoic acid 4 4 1E 1 E 2 2 1 phenyl 1H pyrazole 3 5 diyl bis ethene 2 1 diyl bis 2 methoxyphenol 2 methylpentanedioic acid 1 2 4 dimethylphenyl 2 3 methoxyphenyl diazene 1 benzhydrylamino 3 chloropropan 2 ol 2 Benzyl 1 2 3 4 tetrahydroisoquinoline 8 carboxylic acid 1 Methyl 1 2 3 4 Tetrahydroisoquinoline 8 carboxylic acid